Fluoroquinolone Monotherapy and Combination of a Fluoroquinolone With a β-Lactam
نویسندگان
چکیده
منابع مشابه
Comparison of beta-lactam and macrolide combination therapy versus fluoroquinolone monotherapy in hospitalized Veterans Affairs patients with community-acquired pneumonia.
Data comparing the treatment outcomes of the two most frequently recommended empirical antibiotic regimens for community-acquired pneumonia (CAP)--combination therapy with an extended-spectrum beta-lactam and a macrolide (BL+M) or fluoroquinolone (F) monotherapy--for patients with severe CAP are sparse. The purpose of this study was to compare empirical BL+M combination therapy with F monothera...
متن کاملThe impact of empiric antimicrobial therapy with a β-lactam and fluoroquinolone on mortality for patients hospitalized with severe pneumonia
INTRODUCTION National clinical practice guidelines have recommended specific empiric antimicrobial regimes for patients with severe community-acquired pneumonia. However, evidence confirming improved mortality with many of these regimes is lacking. Our aim was to determine the association between the empiric use of a β-lactam with fluoroquinolone, compared with other recommended antimicrobial t...
متن کاملIs β-Lactam Plus Macrolide More Effective than β-Lactam Plus Fluoroquinolone among Patients with Severe Community-Acquired Pneumonia?: a Systemic Review and Meta-Analysis
Adding either macrolide or fluoroquinolone (FQ) to β-lactam has been recommended for patients with severe community-acquired pneumonia (CAP). However, due to the limited evidence available, there is a question as to the superiority of the two combination therapies. The MEDLINE, EMBASE, Cochrane Central Register, Scopus, and Web of Science databases were searched for systematic review and meta-a...
متن کاملBeta - Lactam and Fluoroquinolone Combination Antibiotic Therapy in Gram - 1 Negative Bacteremia 2 3
1 Department of Medicine, Division of Infectious Diseases, University of Kentucky, 8 Lexington, KY 2 Department of Medicine, Division of Infectious Diseases 3 Department 9 of Health Sciences Research, Division of Biomedical Statistics and Informatics, and 4 10 Department of Laboratory Medicine and Pathology, Division of Clinical Microbiology, 11 College of Medicine, Mayo Clinic, Rochester, MN 5...
متن کاملBeta-lactam and fluoroquinolone combination antibiotic therapy for bacteremia caused by gram-negative bacilli.
The role of combination antibiotic therapy with a beta-lactam and a fluoroquinolone for bacteremia caused by gram-negative bacilli, to our knowledge, has not been previously described. Much of the previous study of combination therapy has included beta-lactams and aminoglycosides. We conducted a large retrospective cohort study to evaluate 28-day all-cause mortality in patients with monomicrobi...
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ژورنال
عنوان ژورنال: Chest
سال: 2019
ISSN: 0012-3692
DOI: 10.1016/j.chest.2019.04.105